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KMID : 0613820120220091261
Journal of Life Science
2012 Volume.22 No. 9 p.1261 ~ p.1267
Effect of Aerobic Exercise and Gym-ball Exercise on the Liver Function Test Index, Adipokines, and Cardiovascular Risk Factors in Obese Children with Nonalcoholic Fatty Liver Disease
Lee Sung-Soo

Abstract
The aim of the present study was to investigate effects of a 12-week aerobic exercise training program and a gym-ball exercise training program on body composition, aspartate aminotransferase (AST), alanine aminotransferase (ALT), adipokines, and cardiovascular risk factors in obese children with nonalcoholic fatty liver disease. The subjects were separated into two groups, an aerobic exercise group (n=10), which practiced moderate aerobic exercise training for 12 weeks, and a gym-ball exercise group (n=13), which practiced resistance exercise training for 12 weeks. The results of the analyses are as follows: Weight, body mass index, and body fat were significantly lower (p<0.01, respectively), whereas the VO©ü max was higher in both groups (p<0.01). Fasting glucose, insulin and HOMA-IR levels were significantly decreased in the gym-ball exercise group (p<0.05), whereas adiponectin, AST, and ALT levels were significantly increased (p<0.05, p<0.001, p<0.001, respectively) in both groups after the 12-week exercise training program. In addition, our results showed that HOMA-IR, insulin, and concentrations of C-reactive protein (CRP) were significantly lower in both groups. They demonstrate that a 12-week program of regular aerobic exercise or gym-ball exercise yields beneficial effects such as an amelioration of cardiovascular risk factors, body indices, and liver function in obese children with nonalcoholic fatty liver disease.
KEYWORD
Adiponectin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), C-Reactive Protein (CRP), homeostasis model assessment of insulin resistance (HOMA-IR)
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